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Biosynthetic Potential-Based Strain Prioritization for Natural Product Discovery: A Showcase for Diterpenoid-Producing Actinomycetes

[Image: see text] Natural products remain the best sources of drugs and drug leads and serve as outstanding small-molecule probes to dissect fundamental biological processes. A great challenge for the natural product community is to discover novel natural products efficiently and cost effectively. H...

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Detalles Bibliográficos
Autores principales: Xie, Pengfei, Ma, Ming, Rateb, Mostafa E., Shaaban, Khaled A., Yu, Zhiguo, Huang, Sheng-Xiong, Zhao, Li-Xing, Zhu, Xiangcheng, Yan, Yijun, Peterson, Ryan M., Lohman, Jeremy R., Yang, Dong, Yin, Min, Rudolf, Jeffrey D., Jiang, Yi, Duan, Yanwen, Shen, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963700/
https://www.ncbi.nlm.nih.gov/pubmed/24484381
http://dx.doi.org/10.1021/np401063s