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Regulation of Sox6 by Cyclin Dependent Kinase 5 in Brain

Cyclin dependent kinase 5 (Cdk5) is a proline-directed Ser/Thr kinase involved in various biological functions during normal brain development and neurodegeneration. In brain, Cdk5 activity is specific to post-mitotic neurons, due to neuronal specific expression of its activator p35. The biological...

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Detalles Bibliográficos
Autores principales: Rudrabhatla, Parvathi, Utreras, Elias, Jaffe, Howard, Kulkarni, Ashok B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963837/
https://www.ncbi.nlm.nih.gov/pubmed/24662752
http://dx.doi.org/10.1371/journal.pone.0089310