Interleukin-6 Modulation of Intestinal Epithelial Tight Junction Permeability Is Mediated by JNK Pathway Activation of Claudin-2 Gene

Defective intestinal epithelial tight junction (TJ) barrier has been shown to be a pathogenic factor in the development of intestinal inflammation. Interleukin-6 (IL-6) is a pleiotropic, pro-inflammatory cytokine which plays an important role in promoting inflammatory response in the gut and in the...

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Detalles Bibliográficos
Autores principales: Al-Sadi, Rana, Ye, Dongmei, Boivin, Michel, Guo, Shuhong, Hashimi, Mariam, Ereifej, Lisa, Ma, Thomas Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963839/
https://www.ncbi.nlm.nih.gov/pubmed/24662742
http://dx.doi.org/10.1371/journal.pone.0085345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963839/
https://www.ncbi.nlm.nih.gov/pubmed/24662742
http://dx.doi.org/10.1371/journal.pone.0085345

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