Comparison of Genome-Wide Association Methods in Analyses of Admixed Populations with Complex Familial Relationships

Population structure is known to cause false-positive detection in association studies. We compared the power, precision, and type-I error rates of various association models in analyses of a simulated dataset with structure at the population (admixture from two populations; P) and family (K) levels...

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Detalles Bibliográficos
Autores principales: Kadri, Naveen K., Guldbrandtsen, Bernt, Sørensen, Peter, Sahana, Goutam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963841/
https://www.ncbi.nlm.nih.gov/pubmed/24662750
http://dx.doi.org/10.1371/journal.pone.0088926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963841/
https://www.ncbi.nlm.nih.gov/pubmed/24662750
http://dx.doi.org/10.1371/journal.pone.0088926

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