Cargando…
Comparison of Genome-Wide Association Methods in Analyses of Admixed Populations with Complex Familial Relationships
Population structure is known to cause false-positive detection in association studies. We compared the power, precision, and type-I error rates of various association models in analyses of a simulated dataset with structure at the population (admixture from two populations; P) and family (K) levels...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963841/ https://www.ncbi.nlm.nih.gov/pubmed/24662750 http://dx.doi.org/10.1371/journal.pone.0088926 |