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Convallatoxin, a Dual Inducer of Autophagy and Apoptosis, Inhibits Angiogenesis In Vitro and In Vivo

Autophagy and apoptosis are important processes that control cellular homeostasis and have been highlighted as promising targets for novel cancer therapies. Here, we identified convallatoxin (CNT), isolated from Antiaris toxicaria, as a dual inducer of autophagy and apoptosis. CNT exerts cytotoxic e...

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Detalles Bibliográficos
Autores principales: Yang, Seung Ya, Kim, Nam Hee, Cho, Yoon Sun, Lee, Hukeun, Kwon, Ho Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963847/
https://www.ncbi.nlm.nih.gov/pubmed/24663328
http://dx.doi.org/10.1371/journal.pone.0091094