A Recombinant Novirhabdovirus Presenting at the Surface the E Glycoprotein from West Nile Virus (WNV) Is Immunogenic and Provides Partial Protection against Lethal WNV Challenge in BALB/c Mice

West Nile Virus (WNV) is a zoonotic mosquito-transmitted flavivirus that can infect and cause disease in mammals including humans. Our study aimed at developing a WNV vectored vaccine based on a fish Novirhabdovirus, the Viral Hemorrhagic Septicemia virus (VHSV). VHSV replicates at temperatures lowe...

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Detalles Bibliográficos
Autores principales: Nzonza, Angella, Lecollinet, Sylvie, Chat, Sophie, Lowenski, Steeve, Mérour, Emilie, Biacchesi, Stéphane, Brémont, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963854/
https://www.ncbi.nlm.nih.gov/pubmed/24663075
http://dx.doi.org/10.1371/journal.pone.0091766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963854/
https://www.ncbi.nlm.nih.gov/pubmed/24663075
http://dx.doi.org/10.1371/journal.pone.0091766

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