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Insights into Ligand Binding to PreQ(1) Riboswitch Aptamer from Molecular Dynamics Simulations

Riboswitches play roles in transcriptional or translational regulation through specific ligand binding of their aptamer domains. Although a number of ligand-bound aptamer complex structures have been solved, it is important to know ligand-free conformations of the aptamers in order to understand the...

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Detalles Bibliográficos
Autores principales: Gong, Zhou, Zhao, Yunjie, Chen, Changjun, Duan, Yong, Xiao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963873/
https://www.ncbi.nlm.nih.gov/pubmed/24663240
http://dx.doi.org/10.1371/journal.pone.0092247