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Insights into Ligand Binding to PreQ(1) Riboswitch Aptamer from Molecular Dynamics Simulations
Riboswitches play roles in transcriptional or translational regulation through specific ligand binding of their aptamer domains. Although a number of ligand-bound aptamer complex structures have been solved, it is important to know ligand-free conformations of the aptamers in order to understand the...
Autores principales: | Gong, Zhou, Zhao, Yunjie, Chen, Changjun, Duan, Yong, Xiao, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963873/ https://www.ncbi.nlm.nih.gov/pubmed/24663240 http://dx.doi.org/10.1371/journal.pone.0092247 |
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