Human Cancer Cells Retain Modest Levels of Enzymatically Active Matriptase Only in Extracellular Milieu following Induction of Zymogen Activation

The type 2 transmembrane serine protease matriptase is broadly expressed in human carcinomas and hematological cancers. The proteolytic activity of matriptase is a potential target of drugs and imaging probes. We assessed the fate of active matriptase following the induction of matriptase zymogen ac...

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Detalles Bibliográficos
Autores principales: Chu, Li-Ling, Xu, Yuan, Yang, Jie-Ru, Hu, Yi-An, Chang, Hsiang-Hua, Lai, Hong-Yu, Tseng, Chun-Che, Wang, Hue-Yu, Johnson, Michael D., Wang, Jehng-Kang, Lin, Chen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963879/
https://www.ncbi.nlm.nih.gov/pubmed/24663123
http://dx.doi.org/10.1371/journal.pone.0092244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963879/
https://www.ncbi.nlm.nih.gov/pubmed/24663123
http://dx.doi.org/10.1371/journal.pone.0092244

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