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Group I PAK Inhibitor IPA-3 Induces Cell Death and Affects Cell Adhesivity to Fibronectin in Human Hematopoietic Cells

P21-activated kinases (PAKs) are involved in the regulation of multiple processes including cell proliferation, adhesion and migration. However, the current knowledge about their function is mainly based on results obtained in adherent cell types. We investigated the effect of group I PAK inhibition...

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Detalles Bibliográficos
Autores principales: Kuželová, Kateřina, Grebeňová, Dana, Holoubek, Aleš, Röselová, Pavla, Obr, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963893/
https://www.ncbi.nlm.nih.gov/pubmed/24664099
http://dx.doi.org/10.1371/journal.pone.0092560