Nucleolar Organization, Ribosomal DNA Array Stability, and Acrocentric Chromosome Integrity Are Linked to Telomere Function

The short arms of the ten acrocentric human chromosomes share several repetitive DNAs, including ribosomal RNA genes (rDNA). The rDNA arrays correspond to nucleolar organizing regions that coalesce each cell cycle to form the nucleolus. Telomere disruption by expressing a mutant version of telomere...

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Detalles Bibliográficos
Autores principales: Stimpson, Kaitlin M., Sullivan, Lori L., Kuo, Molly E., Sullivan, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963894/
https://www.ncbi.nlm.nih.gov/pubmed/24662969
http://dx.doi.org/10.1371/journal.pone.0092432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963894/
https://www.ncbi.nlm.nih.gov/pubmed/24662969
http://dx.doi.org/10.1371/journal.pone.0092432

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