The Pneumococcal Polysaccharide Capsule and Pneumolysin Differentially Affect CXCL8 and IL-6 Release from Cells of the Upper and Lower Respiratory Tract

The polysaccharide capsule and pneumolysin toxin are major virulence factors of the human bacterial pathogen Streptococcus pneumoniae. Colonization of the nasopharynx is asymptomatic but invasion of the lungs can result in invasive pneumonia. Here we show that the capsule suppresses the release of t...

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Detalles Bibliográficos
Autores principales: Küng, Eliane, Coward, William R., Neill, Daniel R., Malak, Hesham A., Mühlemann, Kathrin, Kadioglu, Aras, Hilty, Markus, Hathaway, Lucy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963895/
https://www.ncbi.nlm.nih.gov/pubmed/24664110
http://dx.doi.org/10.1371/journal.pone.0092355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963895/
https://www.ncbi.nlm.nih.gov/pubmed/24664110
http://dx.doi.org/10.1371/journal.pone.0092355

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