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Cell Counting in Human Endobronchial Biopsies - Disagreement of 2D versus 3D Morphometry

QUESTION: Inflammatory cell numbers are important endpoints in clinical studies relying on endobronchial biopsies. Assumption-based bidimensional (2D) counting methods are widely used, although theoretically design-based stereologic three-dimensional (3D) methods alone offer an unbiased quantitative...

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Detalles Bibliográficos
Autores principales: Bratu, Vlad A., Erpenbeck, Veit J., Fehrenbach, Antonia, Rausch, Tanja, Rittinghausen, Susanne, Krug, Norbert, Hohlfeld, Jens M., Fehrenbach, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963904/
https://www.ncbi.nlm.nih.gov/pubmed/24663339
http://dx.doi.org/10.1371/journal.pone.0092510