Endoplasmic Reticulum Stress-Mediated Activation of p38 MAPK, Caspase-2 and Caspase-8 Leads to Abrin-Induced Apoptosis

Abrin from Abrus precatorius plant is a potent protein synthesis inhibitor and induces apoptosis in cells. However, the relationship between inhibition of protein synthesis and apoptosis is not well understood. Inhibition of protein synthesis by abrin can lead to accumulation of unfolded protein in...

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Detalles Bibliográficos
Autores principales: Mishra, Ritu, Karande, Anjali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963924/
https://www.ncbi.nlm.nih.gov/pubmed/24664279
http://dx.doi.org/10.1371/journal.pone.0092586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963924/
https://www.ncbi.nlm.nih.gov/pubmed/24664279
http://dx.doi.org/10.1371/journal.pone.0092586

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