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Protective Effects of Combined Intervention with Adenovirus Vector Mediated IL-10 and IGF-1 Genes on Endogenous Islet β Cells in Nonobese Diabetes Mice with Onset of Type 1 Diabetes Mellitus

OBJECTIVE: To investigate the protective effects of combined intervention with adenovirus vector mediated interleukin 10 (IL-10) and insulin-like growth factor 1 (IGF-1) genes on islet β cells in nonobese diabetes (NOD) mice with type 1 diabetes mellitus (T1D) at early stage. METHODS: Twenty-four fe...

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Detalles Bibliográficos
Autores principales: Zhang, Lijuan, Chen, Yanyan, Li, Cheng, Lin, Xiaojie, Cheng, Xiaoli, Li, Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963932/
https://www.ncbi.nlm.nih.gov/pubmed/24663217
http://dx.doi.org/10.1371/journal.pone.0092616