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Multi-Organ Lesions in Suckling Mice Infected with SARS-Associated Mammalian Reovirus Linked with Apoptosis Induced by Viral Proteins μ1 and σ1

We reported the isolation and characterization of a novel mammalian reassortant reovirus BYD1 that may have played an accomplice role with SARS-coronavirus during the 2003 SARS pandemic. The pathogenic mechanism of this novel reovirus is unknown. Reovirus pathogenicity has been associated with virus...

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Detalles Bibliográficos
Autores principales: Song, Lihua, Lu, Yongfeng, He, Jun, Yu, Yonghui, Zuo, Tingting, Li, Yanwei, Zhu, Hong, Duan, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963933/
https://www.ncbi.nlm.nih.gov/pubmed/24664247
http://dx.doi.org/10.1371/journal.pone.0092678