Cargando…

Improved Functional Expression of Human Cardiac Kv1.5 Channels and Trafficking-Defective Mutants by Low Temperature Treatment

We herein investigated the effect of low temperature exposure on the expression, degradation, localization and activity of human Kv1.5 (hKv1.5). In hKv1.5-expressing CHO cells, the currents were significantly increased when cultured at a reduced temperature (28°C) compared to those observed at 37°C....

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Wei-Guang, Xie, Yu, Toyoda, Futoshi, Matsuura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963980/
https://www.ncbi.nlm.nih.gov/pubmed/24663680
http://dx.doi.org/10.1371/journal.pone.0092923