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Clusterin: a key player in cancer chemoresistance and its inhibition
Clusterin is a heterodimeric disulfide-linked glycoprotein (449 amino acids) isolated in the rat prostate after castration. It is widely distributed in different tissues and highly conserved in species. There are two isoforms (1 and 2) with antagonistic actions regarding apoptosis. Clusterin is impl...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964162/ https://www.ncbi.nlm.nih.gov/pubmed/24672247 http://dx.doi.org/10.2147/OTT.S58622 |