Host Cell Reactivation and Transcriptional Activation of Carboplatin-Modified BRCA1

The breast cancer susceptibility gene 1 (BRCA1) has been shown to maintain genomic stability through multiple functions in the regulation of DNA damage repair and transcription. Its translated BRCT (BRCA1 C-terminal domain) acts as a strong transcriptional activator. BRCA1 damaged by carboplatin tre...

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Detalles Bibliográficos
Autores principales: Ratanaphan, Adisorn, Canyuk, Bhutorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964185/
https://www.ncbi.nlm.nih.gov/pubmed/24678242
http://dx.doi.org/10.4137/BCBCR.S14224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964185/
https://www.ncbi.nlm.nih.gov/pubmed/24678242
http://dx.doi.org/10.4137/BCBCR.S14224

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