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Host Cell Reactivation and Transcriptional Activation of Carboplatin-Modified BRCA1

The breast cancer susceptibility gene 1 (BRCA1) has been shown to maintain genomic stability through multiple functions in the regulation of DNA damage repair and transcription. Its translated BRCT (BRCA1 C-terminal domain) acts as a strong transcriptional activator. BRCA1 damaged by carboplatin tre...

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Detalles Bibliográficos
Autores principales:	Ratanaphan, Adisorn, Canyuk, Bhutorn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964185/ https://www.ncbi.nlm.nih.gov/pubmed/24678242 http://dx.doi.org/10.4137/BCBCR.S14224

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