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Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing

Radiation therapy (RT) is used for local tumor control through direct killing of tumor cells. Radiation-induced cell death can trigger tumor antigen-specific immune responses, but these are often noncurative. Radiation has been demonstrated to induce immunogenic modulation (IM) in various tumor type...

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Detalles Bibliográficos
Autores principales: Gameiro, Sofia R., Jammed, Momodou L., Wattenberg, Max M., Tsang, Kwong Y., Ferrone, Soldano, Hodge, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964216/
https://www.ncbi.nlm.nih.gov/pubmed/24480782