HIF-1α downregulation and apoptosis in hypoxic prostate tumor cells infected with oncolytic Mammalian Orthoreovirus

Hypoxia has emerged as one of the most important drivers of tumor aggression, metastasis, and poor clinical outcome in many cancers. In prostate cancer (PCa), hypoxia has been strongly correlated to biochemical failure and local recurrence. However, current PCa treatment options do not address hypox...

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Detalles Bibliográficos
Autores principales: Gupta-Saraf, Pooja, Miller, Cathy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964229/
https://www.ncbi.nlm.nih.gov/pubmed/24504474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964229/
https://www.ncbi.nlm.nih.gov/pubmed/24504474

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