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Among 45 variants in 11 genes, HDM2 promoter polymorphisms emerge as new candidate biomarker associated with radiation toxicity

Due to individual variations in radiosensitivity, biomarkers are needed to tailor radiation treatment to cancer patients. Since single nucleotide polymorphisms (SNPs) are frequent in human, we hypothesized that SNPs in genes that mitigate the radiation response are associated with radiotoxicity, in...

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Detalles Bibliográficos
Autores principales: Alsbeih, Ghazi, El-Sebaie, Medhat, Al-Rajhi, Nasser, Al-Harbi, Najla, Al-Hadyan, Khaled, Al-Qahtani, Sara, Alsubael, Mohammad, Al-Shabanah, Mohammad, Moftah, Belal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964253/
https://www.ncbi.nlm.nih.gov/pubmed/28324443
http://dx.doi.org/10.1007/s13205-013-0135-3