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Five Transcription Factors and FGF Pathway Inhibition Efficiently Induce Erythroid Differentiation in the Epiblast

Primitive erythropoiesis follows a stereotypic developmental program of mesoderm ventralization and internalization, hemangioblast formation and migration, and erythroid lineage specification. Induction of erythropoiesis is inefficient in either ES/iPS cells in vitro or nonhemangioblast cell populat...

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Detalles Bibliográficos
Autores principales: Weng, Wei, Sheng, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964278/
https://www.ncbi.nlm.nih.gov/pubmed/24672750
http://dx.doi.org/10.1016/j.stemcr.2014.01.019