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Coordination of Engineered Factors with TET1/2 Promotes Early-Stage Epigenetic Modification during Somatic Cell Reprogramming

Somatic cell reprogramming toward induced pluripotent stem cells (iPSCs) holds great promise in future regenerative medicine. However, the reprogramming process mediated by the traditional defined factors (OSMK) is slow and extremely inefficient. Here, we develop a combination of modified reprogramm...

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Detalles Bibliográficos
Autores principales: Zhu, Gengzhen, Li, Yujing, Zhu, Fei, Wang, Tao, Jin, Wensong, Mu, Wei, Lin, Wei, Tan, Weiqi, Li, Wenqi, Street, R. Craig, Peng, Siying, Zhang, Jian, Feng, Yue, Warren, Stephen T., Sun, Qinmiao, Jin, Peng, Chen, Dahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964280/
https://www.ncbi.nlm.nih.gov/pubmed/24672749
http://dx.doi.org/10.1016/j.stemcr.2014.01.012