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Lgr5-Positive Supporting Cells Generate New Hair Cells in the Postnatal Cochlea

The prevalence of hearing loss after damage to the mammalian cochlea has been thought to be due to a lack of spontaneous regeneration of hair cells, the primary receptor cells for sound. Here, we show that supporting cells, which surround hair cells in the normal cochlear epithelium, differentiate i...

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Detalles Bibliográficos
Autores principales: Bramhall, Naomi F., Shi, Fuxin, Arnold, Katrin, Hochedlinger, Konrad, Edge, Albert S.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964281/
https://www.ncbi.nlm.nih.gov/pubmed/24672754
http://dx.doi.org/10.1016/j.stemcr.2014.01.008