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Engineered Biomaterials Control Differentiation and Proliferation of Human-Embryonic-Stem-Cell-Derived Cardiomyocytes via Timed Notch Activation

For cell-based treatments of myocardial infarction, a better understanding of key developmental signaling pathways and more robust techniques for producing cardiomyocytes are required. Manipulation of Notch signaling has promise as it plays an important role during cardiovascular development, but pr...

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Detalles Bibliográficos
Autores principales: Tung, Jason C., Paige, Sharon L., Ratner, Buddy D., Murry, Charles E., Giachelli, Cecilia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964284/
https://www.ncbi.nlm.nih.gov/pubmed/24672751
http://dx.doi.org/10.1016/j.stemcr.2014.01.011