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Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells

The availability of human pluripotent stem cells (hPSCs) offers the opportunity to generate lineage-specific cells to investigate mechanisms of human diseases specific to brain regions. Here, we report a differentiation paradigm for hPSCs that enriches for hippocampal dentate gyrus (DG) granule neur...

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Detalles Bibliográficos
Autores principales: Yu, Diana Xuan, Di Giorgio, Francesco Paolo, Yao, Jun, Marchetto, Maria Carolina, Brennand, Kristen, Wright, Rebecca, Mei, Arianna, Mchenry, Lauren, Lisuk, David, Grasmick, Jaeson Michael, Silberman, Pedro, Silberman, Giovanna, Jappelli, Roberto, Gage, Fred H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964286/
https://www.ncbi.nlm.nih.gov/pubmed/24672753
http://dx.doi.org/10.1016/j.stemcr.2014.01.009