Counteracting Activities of OCT4 and KLF4 during Reprogramming to Pluripotency

Differentiated cells can be reprogrammed into induced pluripotent stem cells (iPSCs) after overexpressing four transcription factors, of which Oct4 is essential. To elucidate the role of Oct4 during reprogramming, we investigated the immediate transcriptional response to inducible Oct4 overexpressio...

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Detalles Bibliográficos
Autores principales: Tiemann, Ulf, Marthaler, Adele Gabriele, Adachi, Kenjiro, Wu, Guangming, Fischedick, Gerrit Ulf Lennart, Araúzo-Bravo, Marcos Jesús, Schöler, Hans Robert, Tapia, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964287/
https://www.ncbi.nlm.nih.gov/pubmed/24672757
http://dx.doi.org/10.1016/j.stemcr.2014.01.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964287/
https://www.ncbi.nlm.nih.gov/pubmed/24672757
http://dx.doi.org/10.1016/j.stemcr.2014.01.005

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