Obesity-Induced Infertility and Hyperandrogenism Are Corrected by Deletion of the Insulin Receptor in the Ovarian Theca Cell

Women with polycystic ovary syndrome (PCOS) exhibit elevated androgen levels, oligoanovulation, infertility, and insulin resistance in metabolic tissues. The aims of these studies were to determine the role of insulin signaling in the development and function of ovarian theca cells and the pathophys...

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Detalles Bibliográficos
Autores principales: Wu, Sheng, Divall, Sara, Nwaopara, Amanda, Radovick, Sally, Wondisford, Fredric, Ko, CheMyong, Wolfe, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964497/
https://www.ncbi.nlm.nih.gov/pubmed/24379345
http://dx.doi.org/10.2337/db13-1514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964497/
https://www.ncbi.nlm.nih.gov/pubmed/24379345
http://dx.doi.org/10.2337/db13-1514

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