P38 Plays an Important Role in Glucolipotoxicity-Induced Apoptosis in INS-1 Cells

Objectives. The mechanism underlying the regulation of glucolipotoxicity-induced apoptosis by MAPKs was examined in INS-1 cells. Methods. The rat insulinoma cell line INS-1 was cotreated with glucose (30 mM) and palmitic acid (0.2 mM) (GLU+PA). Apoptosis was assessed by cell morphology and detection...

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Detalles Bibliográficos
Autores principales: Zhou, Lingli, Cai, Xiaoling, Han, Xueyao, Ji, Linong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964802/
https://www.ncbi.nlm.nih.gov/pubmed/24734256
http://dx.doi.org/10.1155/2014/834528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964802/
https://www.ncbi.nlm.nih.gov/pubmed/24734256
http://dx.doi.org/10.1155/2014/834528

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