Intestinal crypt homeostasis revealed at single stem cell level by in vivo live-imaging

The rapid turnover of the mammalian intestinal epithelium is supported by stem cells located around the base of the crypt(1). Alongside Lgr5, intestinal stem cells have been associated with various markers, which are expressed heterogeneously within the crypt base region(1-6). Previous quantitative...

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Detalles Bibliográficos
Autores principales: Ritsma, Laila, Ellenbroek, Saskia I.J., Zomer, Anoek, Snippert, Hugo J., de Sauvage, Frederic J., Simons, Benjamin D., Clevers, Hans, van Rheenen, Jacco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964820/
https://www.ncbi.nlm.nih.gov/pubmed/24531760
http://dx.doi.org/10.1038/nature12972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964820/
https://www.ncbi.nlm.nih.gov/pubmed/24531760
http://dx.doi.org/10.1038/nature12972

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