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G-Quadruplex DNA as a Molecular Target for Induced Synthetic Lethality in Cancer Cells
[Image: see text] Synthetic lethality is a genetic concept in which cell death is induced by the combination of mutations in two sensitive genes, while mutation of either gene alone is not sufficient to affect cell survival. Synthetic lethality can also be achieved “chemically” by combination of dru...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964824/ https://www.ncbi.nlm.nih.gov/pubmed/23782415 http://dx.doi.org/10.1021/ja404868t |