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Intravitreal and Subconjunctival Melphalan for Retinoblastoma in Transgenic Mice

Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg intravitreal injection of melphalan, 100 mcg...

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Detalles Bibliográficos
Autores principales: Shah, Nisha V., Pham, D. G., Murray, T. G., Decatur, C., Hernandez, E., Shah, Nikesh N., Cavalcante, M., Houston, S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964900/
https://www.ncbi.nlm.nih.gov/pubmed/24734170
http://dx.doi.org/10.1155/2014/829879