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Principles of ion recognition in RNA: insights from the group II intron structures

Metal ions promote both RNA folding and catalysis, thus being essential in stabilizing the structure and determining the function of large RNA molecules, including group II introns. The latter are self-splicing metalloribozymes, containing a heteronuclear four-metal-ion center within the active site...

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Detalles Bibliográficos
Autores principales: Marcia, Marco, Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964913/
https://www.ncbi.nlm.nih.gov/pubmed/24570483
http://dx.doi.org/10.1261/rna.043414.113