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Rat1p maintains RNA polymerase II CTD phosphorylation balance

In S. cerevisiae, the 5′-3′ exonuclease Rat1p partakes in transcription termination. Although Rat1p-mediated RNA degradation has been suggested to play a role for this activity, the exact mechanisms by which Rat1p helps release RNA polymerase II (RNAPII) from the DNA template are poorly understood....

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Detalles Bibliográficos
Autores principales: Jimeno-González, Silvia, Schmid, Manfred, Malagon, Francisco, Haaning, Line Lindegaard, Jensen, Torben Heick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964916/
https://www.ncbi.nlm.nih.gov/pubmed/24501251
http://dx.doi.org/10.1261/rna.041129.113