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Diverse Mechanisms of Wnt Activation and Effects of Pathway Inhibition on Proliferation of Human Gastric Carcinoma Cells

Human gastric carcinomas are among the most treatment refractory epithelial malignancies. Increased understanding of the underlying molecular aberrations in such tumors could provide insights leading to improved therapeutic approaches. In this study, we characterized diverse genetic aberrations lead...

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Detalles Bibliográficos
Autores principales: Asciutti, Stefania, Akiri, Gal, Grumolato, Luca, Vijayakumar, Sapna, Aaronson, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965355/
https://www.ncbi.nlm.nih.gov/pubmed/21042278
http://dx.doi.org/10.1038/onc.2010.475