Cargando…
Diverse Mechanisms of Wnt Activation and Effects of Pathway Inhibition on Proliferation of Human Gastric Carcinoma Cells
Human gastric carcinomas are among the most treatment refractory epithelial malignancies. Increased understanding of the underlying molecular aberrations in such tumors could provide insights leading to improved therapeutic approaches. In this study, we characterized diverse genetic aberrations lead...
Autores principales: | Asciutti, Stefania, Akiri, Gal, Grumolato, Luca, Vijayakumar, Sapna, Aaronson, Stuart A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965355/ https://www.ncbi.nlm.nih.gov/pubmed/21042278 http://dx.doi.org/10.1038/onc.2010.475 |
Ejemplares similares
-
Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells
por: Liu, Guizhong, et al.
Publicado: (2009) -
β-Catenin-Independent Activation of TCF1/LEF1 in Human Hematopoietic Tumor Cells through Interaction with ATF2 Transcription Factors
por: Grumolato, Luca, et al.
Publicado: (2013) -
THE CANONICAL WNT PATHWAY IN GASTRIC CARCINOMA
por: de OLIVEIRA, Levindo Alves, et al.
Publicado: (2019) -
Extracellular LDLR repeats modulate Wnt signaling activity by promoting LRP6 receptor endocytosis mediated by the Itch E3 ubiquitin ligase
por: Vijayakumar, Sapna, et al.
Publicado: (2017) -
Cir-ITCH inhibits gastric cancer migration, invasion and proliferation by regulating the Wnt/β-catenin pathway
por: Peng, Yang, et al.
Publicado: (2020)