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Effects of High Affinity Leptin Antagonist on Prolactin Receptor Deficient Male Mouse

Hyperprolactinemia occurs during gestation and lactation with marked hyperphagia associated with leptin resistance. Prolactin (PRL) induces the expression of orexigenic neuropeptide Y (NPY) in hypothalamic dorsomedial nucleus (DMH) leading to hyperphagia. Along this line prolactin receptor deficient...

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Detalles Bibliográficos
Autores principales: Carré, Nadège, Solomon, Gili, Gertler, Arieh, Binart, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965386/
https://www.ncbi.nlm.nih.gov/pubmed/24667351
http://dx.doi.org/10.1371/journal.pone.0091422