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Effects of High Affinity Leptin Antagonist on Prolactin Receptor Deficient Male Mouse
Hyperprolactinemia occurs during gestation and lactation with marked hyperphagia associated with leptin resistance. Prolactin (PRL) induces the expression of orexigenic neuropeptide Y (NPY) in hypothalamic dorsomedial nucleus (DMH) leading to hyperphagia. Along this line prolactin receptor deficient...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965386/ https://www.ncbi.nlm.nih.gov/pubmed/24667351 http://dx.doi.org/10.1371/journal.pone.0091422 |