Association of Variants at BCL11A and HBS1L-MYB with Hemoglobin F and Hospitalization Rates among Sickle Cell Patients in Cameroon

BACKGROUND: Genetic variation at loci influencing adult levels of HbF have been shown to modify the clinical course of sickle cell disease (SCD). Data on this important aspect of SCD have not yet been reported from West Africa. We investigated the relationship between HbF levels and the relevant gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Wonkam, Ambroise, Ngo Bitoungui, Valentina J., Vorster, Anna A., Ramesar, Raj, Cooper, Richard S., Tayo, Bamidele, Lettre, Guillaume, Ngogang, Jeanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965431/
https://www.ncbi.nlm.nih.gov/pubmed/24667352
http://dx.doi.org/10.1371/journal.pone.0092506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965431/
https://www.ncbi.nlm.nih.gov/pubmed/24667352
http://dx.doi.org/10.1371/journal.pone.0092506

Ejemplares similares