Pemt Deficiency Ameliorates Endoplasmic Reticulum Stress in Diabetic Nephropathy

Phosphatidylethanolamine N-methyltransferase (Pemt) catalyzes the methylation of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) mainly in the liver. Under an obese state, the upregulation of Pemt induces endoplasmic reticulum (ER) stress by increasing the PC/PE ratio in the liver. We targ...

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Detalles Bibliográficos
Autores principales: Watanabe, Mayu, Nakatsuka, Atsuko, Murakami, Kazutoshi, Inoue, Kentaro, Terami, Takahiro, Higuchi, Chigusa, Katayama, Akihiro, Teshigawara, Sanae, Eguchi, Jun, Ogawa, Daisuke, Watanabe, Eijiro, Wada, Jun, Makino, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965443/
https://www.ncbi.nlm.nih.gov/pubmed/24667182
http://dx.doi.org/10.1371/journal.pone.0092647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965443/
https://www.ncbi.nlm.nih.gov/pubmed/24667182
http://dx.doi.org/10.1371/journal.pone.0092647

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