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Accurate and Economical Detection of ALK Positive Lung Adenocarcinoma with Semiquantitative Immunohistochemical Screening

Right detection of anaplastic lymphoma kinase (ALK) gene rearrangement is pivotal to selection of patients with lung adenocarcinoma for ALK-targeted therapy. We explored the potential of combination of immunohistochemistry (IHC) screening and fluorescence in situ hybridization (FISH) as an affordabl...

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Detalles Bibliográficos
Autores principales: Zhou, Jianya, Zhao, Jing, Sun, Ke, Wang, Bo, Wang, Lijun, Chen, Xi, Zheng, Jing, You, Qihan, Wang, Xiaoling, Ding, Wei, Zhou, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965450/
https://www.ncbi.nlm.nih.gov/pubmed/24667320
http://dx.doi.org/10.1371/journal.pone.0092828