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Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission

Over 80% of sexual HIV-1 transmissions originate from a single viral variant, but the underlying basis for this transmission bottleneck remains to be elucidated. Nonhuman primate models of mucosal virus transmission allow opportunities to gain insight into the basis of this mucosal bottleneck. We us...

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Detalles Bibliográficos
Autores principales: Smedley, Jeremy, Turkbey, Baris, Bernardo, Marcelino L., Del Prete, Gregory Q., Estes, Jacob D., Griffiths, Gary L., Kobayashi, Hisataka, Choyke, Peter L., Lifson, Jeffrey D., Keele, Brandon F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965472/
https://www.ncbi.nlm.nih.gov/pubmed/24667371
http://dx.doi.org/10.1371/journal.pone.0092830