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Lack of Association between Intact/Deletion Polymorphisms of the APOBEC3B Gene and HIV-1 Risk

OBJECTIVE: The human APOBEC3 family of proteins potently restricts HIV-1 replication APOBEC3B, one of the family genes, is frequently deleted in human populations. Two previous studies reached inconsistent conclusions regarding the effects of APOBEC3B loss on HIV-1 acquisition and pathogenesis. Ther...

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Detalles Bibliográficos
Autores principales: Imahashi, Mayumi, Izumi, Taisuke, Watanabe, Dai, Imamura, Junji, Matsuoka, Kazuhiro, Ode, Hirotaka, Masaoka, Takashi, Sato, Kei, Kaneko, Noriyo, Ichikawa, Seiichi, Koyanagi, Yoshio, Takaori-Kondo, Akifumi, Utsumi, Makoto, Yokomaku, Yoshiyuki, Shirasaka, Takuma, Sugiura, Wataru, Iwatani, Yasumasa, Naoe, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965477/
https://www.ncbi.nlm.nih.gov/pubmed/24667791
http://dx.doi.org/10.1371/journal.pone.0092861