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Dual Effect of a Polymorphism in the Macrophage Migration Inhibitory Factor Gene Is Associated with New-Onset Graves Disease in a Taiwanese Chinese Population

Graves disease (GD) is an autoimmune disease. Macrophage migration inhibitory factor (MIF) is a potent cytokine that plays an important role in the regulation of immune responses. Two polymorphisms in the promoter region of MIF, rs5844572 and rs755622, are known to affect MIF expression. The purpose...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Huei, Chen, Ching-Chu, Yang, Chen-Ming, Chen, Yi-Ju, Tsai, Fuu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965479/
https://www.ncbi.nlm.nih.gov/pubmed/24667663
http://dx.doi.org/10.1371/journal.pone.0092849