Sulforaphane Induces Oxidative Stress and Death by p53-Independent Mechanism: Implication of Impaired Glutathione Recycling

Sulforaphane (SFN) is a naturally-occurring isothiocyanate best known for its role as an indirect antioxidant. Notwithstanding, in different cancer cell lines, SFN may promote the accumulation of reactive oxygen species (ROS) and cause cell death e.g. by apoptosis. Osteosarcoma often becomes chemore...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferreira de Oliveira, José Miguel P., Costa, Maria, Pedrosa, Tiago, Pinto, Pedro, Remédios, Catarina, Oliveira, Helena, Pimentel, Francisco, Almeida, Luís, Santos, Conceição
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965485/
https://www.ncbi.nlm.nih.gov/pubmed/24667842
http://dx.doi.org/10.1371/journal.pone.0092980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965485/
https://www.ncbi.nlm.nih.gov/pubmed/24667842
http://dx.doi.org/10.1371/journal.pone.0092980

Ejemplares similares