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Activation of Platelet-Derived Growth Factor Receptor Alpha Contributes to Liver Fibrosis

Chronic liver injury leads to fibrosis, cirrhosis, and loss of liver function. Liver cirrhosis is the 12th leading cause of death in the United States, and it is the primary risk factor for developing liver cancer. Fibrosis and cirrhosis result from activation of hepatic stellate cells (HSCs), which...

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Detalles Bibliográficos
Autores principales: Hayes, Brian J., Riehle, Kimberly J., Shimizu-Albergine, Masami, Bauer, Renay L., Hudkins, Kelly L., Johansson, Fredrik, Yeh, Matthew M., Mahoney, William M., Yeung, Raymond S., Campbell, Jean S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965491/
https://www.ncbi.nlm.nih.gov/pubmed/24667490
http://dx.doi.org/10.1371/journal.pone.0092925