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Activation of Platelet-Derived Growth Factor Receptor Alpha Contributes to Liver Fibrosis
Chronic liver injury leads to fibrosis, cirrhosis, and loss of liver function. Liver cirrhosis is the 12th leading cause of death in the United States, and it is the primary risk factor for developing liver cancer. Fibrosis and cirrhosis result from activation of hepatic stellate cells (HSCs), which...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965491/ https://www.ncbi.nlm.nih.gov/pubmed/24667490 http://dx.doi.org/10.1371/journal.pone.0092925 |