Intrinsic Susceptibility MRI Identifies Tumors with ALK(F1174L) Mutation in Genetically-Engineered Murine Models of High-Risk Neuroblastoma

The early identification of children presenting ALK(F1174L)-mutated neuroblastoma, which are associated with resistance to the promising ALK inhibitor crizotinib and a marked poorer prognosis, has become a clinical priority. In comparing the radiology of the novel Th-ALK(F1174L)/Th-MYCN and the well...

Descripción completa

Detalles Bibliográficos
Autores principales: Jamin, Yann, Glass, Laura, Hallsworth, Albert, George, Rani, Koh, Dow-Mu, Pearson, Andrew D. J., Chesler, Louis, Robinson, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965493/
https://www.ncbi.nlm.nih.gov/pubmed/24667968
http://dx.doi.org/10.1371/journal.pone.0092886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965493/
https://www.ncbi.nlm.nih.gov/pubmed/24667968
http://dx.doi.org/10.1371/journal.pone.0092886

Ejemplares similares