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Depletion of White Adipose Tissue in Cancer Cachexia Syndrome Is Associated with Inflammatory Signaling and Disrupted Circadian Regulation

Involuntary weight loss in patients with cancer is the hallmark of cancer cachexia. The etiology of cachexia is multifactorial involving loss of skeletal muscle and adipose tissue associated with high systemic levels of acute phase proteins and inflammatory cytokines. While muscle wasting overtly im...

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Detalles Bibliográficos
Autores principales: Tsoli, Maria, Schweiger, Martina, Vanniasinghe, Anne S., Painter, Arran, Zechner, Rudolf, Clarke, Stephen, Robertson, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965507/
https://www.ncbi.nlm.nih.gov/pubmed/24667661
http://dx.doi.org/10.1371/journal.pone.0092966